Operational challenges in managing Isoniazid Preventive Therapy in child contacts : a high-burden setting perspective

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dc.contributor.authorVan Wyk, Susan S.
dc.contributor.authorReid, Anthony J.
dc.contributor.authorMandalakas, Anna M.
dc.contributor.authorEnarson, Donald A.
dc.contributor.authorBeyers, Nulda
dc.contributor.authorMorrison, Julie
dc.contributor.authorHesseling, Anneke C.
dc.date.accessioned2011-08-25T10:13:06Z
dc.date.available2011-08-25T10:13:06Z
dc.date.issued2011-07-08
dc.date.updated2011-08-05T05:04:57Z
dc.descriptionThe original publication is available at http://www.biomedcentral.com/1471-2458/11/544en_ZA
dc.description.abstractAbstract Background The study was conducted at a high TB-HIV burden primary health community clinic in Cape Town, South Africa. We describe the management of children under five years of age in household contact with a smear and/or culture-positive adult TB case. Methods This study was a record review of routinely-collected programme data. Results A total of 1094 adult TB case folders were reviewed. From all identified contacts, 149 children should have received IPT based on local guidelines; in only 2/149 IPT was initiated. Management of child contacts of sputum smear and/or culture-positive compared to sputum-negative TB patients were similar. Conclusions IPT delivery to children remains an operational challenge, especially in high TB-HIV burden communities. A tool to improve IPT management and targeting sputum smear and/or culture-positive TB child contacts may overcome some of these challenges and should be developed and piloted in such settings.en_ZA
dc.description.versionPublishers' Versionen_ZA
dc.format.extent6 p.
dc.identifier.citationVan Wyk, S. et al, 2011, Operational challenges in managing Isoniazid Preventive Therapy in child contacts: a highburden setting perspective, BMC Public Health, 11(1):544, 1-6, http://www.biomedcentral.com/1471-2458/11/544en_ZA
dc.identifier.issnhttp://dx.doi.org/10.1186/1471-2458-11-544
dc.identifier.urihttp://hdl.handle.net/10019.1/16294
dc.language.isoen_ZAen_ZA
dc.language.rfc3066en
dc.rights.holderBioMed Central Ltd.en_ZA
dc.rights.holderAuthor retain copyrighten_ZA
dc.subjectIsoniazid preventive therapyen
dc.subjectChildren -- Testing for tuberculosis -- South Africa -- Western Capeen
dc.titleOperational challenges in managing Isoniazid Preventive Therapy in child contacts : a high-burden setting perspectiveen_ZA
dc.typeArticleen_ZA
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Research Articles (Paediatrics and Child Health)