Operational challenges in managing Isoniazid Preventive Therapy in child contacts : a high-burden setting perspective
Date
2011-07-08
Authors
Van Wyk, Susan S.
Reid, Anthony J.
Mandalakas, Anna M.
Enarson, Donald A.
Beyers, Nulda
Morrison, Julie
Hesseling, Anneke C.
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Abstract Background The study was conducted at a high TB-HIV burden primary health community clinic in Cape Town, South Africa. We describe the management of children under five years of age in household contact with a smear and/or culture-positive adult TB case. Methods This study was a record review of routinely-collected programme data. Results A total of 1094 adult TB case folders were reviewed. From all identified contacts, 149 children should have received IPT based on local guidelines; in only 2/149 IPT was initiated. Management of child contacts of sputum smear and/or culture-positive compared to sputum-negative TB patients were similar. Conclusions IPT delivery to children remains an operational challenge, especially in high TB-HIV burden communities. A tool to improve IPT management and targeting sputum smear and/or culture-positive TB child contacts may overcome some of these challenges and should be developed and piloted in such settings.
Description
The original publication is available at http://www.biomedcentral.com/1471-2458/11/544
Keywords
Isoniazid preventive therapy, Children -- Testing for tuberculosis -- South Africa -- Western Cape
Citation
Van Wyk, S. et al, 2011, Operational challenges in managing Isoniazid Preventive Therapy in child contacts: a highburden setting perspective, BMC Public Health, 11(1):544, 1-6, http://www.biomedcentral.com/1471-2458/11/544