The complete genome sequence of the African buffalo (Syncerus caffer)

Simple item page
dc.contributor.authorGlanzmann, Brigitteen_ZA
dc.contributor.authorMoller, Marloen_ZA
dc.contributor.authorLe Roex, Nikkien_ZA
dc.contributor.authorTromp, Gerarden_ZA
dc.contributor.authorHoal, Eileen G.en_ZA
dc.contributor.authorVan Helden, Paul D.en_ZA
dc.date.accessioned2017-01-23T08:00:46Z
dc.date.available2017-01-23T08:00:46Z
dc.date.issued2016-12-07
dc.date.updated2016-12-09T12:01:49Z
dc.descriptionCITATION: Glanzmann, B., et al. 2016. The complete genome sequence of the African buffalo (Syncerus caffer). BMC Genomics, 17:1001, doi:10.1186/s12864-016-3364-0.
dc.descriptionThe original publication is available at http://bmcgenomics.biomedcentral.com
dc.descriptionPublication of this article was funded by the Stellenbosch University Open Access Fund.
dc.description.abstractBackground: The African buffalo (Syncerus caffer) is an important role player in the savannah ecosystem. It has become a species of relevance because of its role as a wildlife maintenance host for an array of infectious and zoonotic diseases some of which include corridor disease, foot-and-mouth disease and bovine tuberculosis. To date, no complete genome sequence for S. caffer had been available for study and the genomes of other species such as the domestic cow (Bos taurus) had been used as a proxy for any genetics analysis conducted on this species. Here, the high coverage genome sequence of the African buffalo (S. caffer) is presented. Results: A total of 19,765 genes were predicted and 19,296 genes could be successfully annotated to S. caffer while 469 genes remained unannotated. Moreover, in order to extend a detailed annotation of S. caffer, gene clusters were constructed using twelve additional mammalian genomes. The S. caffer genome contains 10,988 gene clusters, of which 62 are shared exclusively between B. taurus and S. caffer. Conclusions: This study provides a unique genomic perspective for the S. caffer, allowing for the identification of novel variants that may play a role in the natural history and physiological adaptations.
dc.description.sponsorshipNational Research Foundation of South Africa
dc.description.sponsorshipSouth African Medical Research Council
dc.description.sponsorshipStellenbosch University
dc.description.versionPublisher's version
dc.format.extent7 pages
dc.identifier.citationGlanzmann, B., et al. 2016. The complete genome sequence of the African buffalo (Syncerus caffer). BMC Genomics, 17:1001, doi:10.1186/s12864-016-3364-0
dc.identifier.issn1471-2164 (online)
dc.identifier.otherdoi:10.1186/s12864-016-3364-0
dc.identifier.urihttp://hdl.handle.net/10019.1/100496
dc.language.isoen_ZAen_ZA
dc.publisherBioMed Central
dc.rights.holderAuthors retain copyright
dc.subjectGenomesen_ZA
dc.subjectAfrican buffaloen_ZA
dc.subjectSyncerus cafferen_ZA
dc.subjectBos taurusen_ZA
dc.subjectGenetic variationen_ZA
dc.titleThe complete genome sequence of the African buffalo (Syncerus caffer)en_ZA
dc.typeArticle
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
glanzmann_complete_2016.pdf
Size:
571.16 KB
Format:
Adobe Portable Document Format
Description:
Download article
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.95 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Research Articles (Molecular Biology and Human Genetics)