Retinopathy of prematurity screening criteria and workload implications at Tygerberg Children’s Hospital, South Africa : a cross-sectional study

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dc.contributor.authorKift, Elsime Visseren_ZA
dc.contributor.authorFreeman, Nicolaen_ZA
dc.contributor.authorCook, Colinen_ZA
dc.contributor.authorMyer, Landonen_ZA
dc.date.accessioned2017-02-10T13:56:50Z
dc.date.available2017-02-10T13:56:50Z
dc.date.issued2016-05-12
dc.descriptionCITATION: Kift, E. V., Freeman, N., Cook, C. & Myer, L. 2016. Retinopathy of prematurity screening criteria and workload implications at Tygerberg Children’s Hospital, South Africa : a cross-sectional study. South African Medical Journal, 106(6):602-606, doi:10.7196/SAMJ.2016.v106i6.10358.
dc.descriptionThe original publication is available at http://www.samj.org.za
dc.description.abstractBackground. Screening guidelines for retinopathy of prematurity (ROP) used in high-income countries are not appropriate for middle- income countries, and screening requirements may vary even between units within one city. Objective. To determine optimal ROP screening criteria, and its workload implications, for Tygerberg Children’s Hospital (TCH), Cape Town, South Africa. Methods. This cross-sectional study included premature infants screened for ROP at TCH from 1 January 2009 to 31 December 2014. Logistic regression analysis for prediction and classification was performed. Predictors were birth weight (BW) and gestational age (GA). Endpoints were clinically significant ROP (CSROP) and type 1 ROP (T1ROP). Results. Of 1 104 eligible infants, 33.4% had ROP (CSROP 9.1%, T1ROP 2.5%). All T1ROP infants received laser therapy. The number of screening examinations was inversely correlated with GA and BW. The number needed to screen to identify one infant requiring treatment was 41 (entailing 83 examinations, 4 screening hours, one technician and three doctors). Screening infants with a GA of ≤28 weeks or a BW of <1 000 g would have detected all infants with T1ROP but missed two outliers with CSROP. These outliers would only have been detected with a GA of ≤32 weeks or a BW <1 500 g. Conclusions. Detection of infants with T1ROP is resource intensive. Larger infants require screening to include a few outliers, but they require fewer examinations than smaller infants. Making local screening criteria narrower on the basis of a limited evidence base may be dangerous. Risk factors for CSROP in larger infants need to be researched.en_ZA
dc.description.abstractAFRIKAANSE OPSOMMING: Geen opsomming beskikbaaraf_ZA
dc.description.urihttp://www.samj.org.za/index.php/samj/article/view/10358
dc.description.versionPublisher's version
dc.format.extent5 pages
dc.identifier.citationKift, E. V., Freeman, N., Cook, C. & Myer, L. 2016. Retinopathy of prematurity screening criteria and workload implications at Tygerberg Children’s Hospital, South Africa : a cross-sectional study. South African Medical Journal, 106(6):602-606, doi:10.7196/SAMJ.2016.v106i6.10358.
dc.identifier.issn2078-5135 (online)
dc.identifier.issn0256-9574 (print)
dc.identifier.otherdoi:10.7196/SAMJ.2016.v106i6.10358
dc.identifier.urihttp://hdl.handle.net/10019.1/100622
dc.language.isoen_ZAen_ZA
dc.publisherHealth & Medical Publishing Group
dc.rights.holderAuthors retain copyright
dc.subjectRetinopathy of prematurityen_ZA
dc.subjectMedical screeningen_ZA
dc.subjectPremature infants -- Medical screeningen_ZA
dc.titleRetinopathy of prematurity screening criteria and workload implications at Tygerberg Children’s Hospital, South Africa : a cross-sectional studyen_ZA
dc.typeArticleen_ZA
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