The possible role of endogenous digitalis-like substance in the causation of pre-eclampsia

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dc.contributor.authorBeyers, A. D.
dc.contributor.authorOdendaal, H. J.
dc.contributor.authorSpruyt, L. L.
dc.contributor.authorParkin, D. P.
dc.date.accessioned2011-03-18T14:59:45Z
dc.date.available2011-03-18T14:59:45Z
dc.date.issued1984-06
dc.descriptionThe original publication is available at http://www.samj.org.za
dc.description.abstractDigoxin levels have been reported in neonatal blood when neither the mother nor the baby had received digoxin. An endogenous digoxin-like substance (DLS) that may be causally related to hypertension has been described. Using a commercially available radio-immunoassay kit, we investigated the presence of an immunoreactive DLS in 21 pre-eclamptic mothers, 36 mothers with normal blood pressure (the control group) and their infants. We found mean DLS levels to be higher in cord blood from infants born to the pre-eclamptic mothers than in cord blood from those born to mothers in the control group. Levels were also higher in cord blood than in maternal blood in both the pre-eclamptic and the control groups. DLS seems to be associated with pre-eclampsia. Although further work is needed for verification, a hypothesis on the possible role of DLS in the causation of pre-eclampsia is presented.en_ZA
dc.description.versionPublishers' version
dc.format.extent3 p.
dc.identifier.citationBeyers, A. D. et al. 1984. The possible role of endogenous digitalis-like substance in the causation of pre-eclampsia. South African Medical Journal, 2 June: 883-885.
dc.identifier.issn2078-5135 (online) 0256-9574 (print)
dc.identifier.urihttp://hdl.handle.net/10019.1/8028
dc.language.isoen
dc.publisherHealth and Medical Publishing Group -- HMPG
dc.rights.holderThe authors
dc.subjectPreeclampsiaen_ZA
dc.titleThe possible role of endogenous digitalis-like substance in the causation of pre-eclampsiaen_ZA
dc.typeArticle
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