Early detection of poor fetal prognosis by serial Doppler velocimetry in high-risk pregnancies

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dc.contributor.authorPattinson, R. C.en_ZA
dc.contributor.authorBrink, A. L.en_ZA
dc.contributor.authorDe Wet, P. E.en_ZA
dc.contributor.authorOdendaal, H. J.en_ZA
dc.date.accessioned2011-03-18T14:57:17Z
dc.date.available2011-03-18T14:57:17Z
dc.date.issued1991
dc.descriptionCITATION: Pattinson, R. C. et al. 1991. Early detection of poor fetal prognosis by serial Doppler velocimetry in high-risk pregnancies. South African Medical Journal, 80:428-431.
dc.descriptionThe original publication is available at http://www.samj.org.za
dc.description.abstractFifty-three high-risk pregnancies were followed up serially with Doppler velocimetry of the umbilical artery and uterine vessels from early on to investigate whether abnormalities in Doppler waveforms can predict the outcome of pregnancy accurately before other clinical signs develop. Results of Doppler velocimetry were withheld from the clinicians managing the patients. When the absence of end-diastolic velocities was first detected (in 13 fetuses) (AEDV group) there was no clinical difference between these pregnancies and those in which enddiastolic velocities were present (EDV group). Nine of the 13 fetuses with AEDVs died, compared with 3 of 40 with EDVs (P < 0,0001). In deaths associated with AEDVs, the latter were detected a median of 5,5 (range 3-11) weeks before death and are present from the first Doppler examination. In the 4 fetuses with AEDVs that survived, the AEDVs were not persistent. The only significant association of Doppler velocimetry of the uterine vessels was with proteinuric hypertension (P < 0,05), but the prediction was not strong enough to be of clinical value. Persistent AEDVs of the umbilical artery are an accurate predictor of poor fetal outcome and occur before other clinical signs of impending problems.
dc.description.versionPublisher’s version
dc.format.extent4 pages
dc.identifier.issn2078-5135 (online)
dc.identifier.issn0256-9574 (print)
dc.identifier.urihttp://hdl.handle.net/10019.1/7309
dc.language.isoen
dc.publisherHealth & Medical Publishing Group
dc.rights.holderSouth African Medical Journal
dc.subjectPregnancyen_ZA
dc.titleEarly detection of poor fetal prognosis by serial Doppler velocimetry in high-risk pregnanciesen_ZA
dc.typeArticle
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