Modelling the trends of inpatient and outpatient rehabilitation for methamphetamine in the Western Cape province of South Africa
Date
2015-12-18
Journal Title
Journal ISSN
Volume Title
Publisher
BioMed Central
Abstract
Background: Dependence on methamphetamine remains one of the major health and social problem in the Western
Cape province of South Africa. We consider a mathematical model that takes into account two forms of rehabilitation,
namely; inpatient and outpatient. We examine the trends of these two types of rehabilitation. We also seek to
investigate the global dynamics of the developed methamphetamine epidemic model.
Methods: The model is designed by likening the initiation process to an infection that spreads in a community
through interactions between methamphetamine users and non-users. We make use of Lyapunov functions obtained
from a suitable combination of common quadratic and Volterra-type functions to establish the global stability of the
methamphetamine-persistent steady state. The least squares curve fit routine (lsqcurvefit) in Matlab with optimization
is used to estimate the parameter values.
Results: The model analysis shows that the model has two equilibria, the methamphetamine free equilibrium and
the methamphetamine persistent equilibrium, that are both globally stable when the threshold Ra < 1 and Ra > 1,
respectively. Upon fitting the model to data on drug users under rehabilitation, parameter values that give the best fit
were obtained. The projections carried out the long term trends of these forms of rehabilitation.
Conclusion: The results suggest that inpatient rehabilitation programs have an increased potential of enhancing the
chances of recovery for methamphetamine addicts.
Description
CITATION: Mushanyu, J., Nyabadza, F. & Stewart, A. G. R. 2015. Modelling the trends of inpatient and outpatient rehabilitation for methamphetamine in the Western Cape province of South Africa. BMC Research Notes, 8:797, doi:10.1186/s13104-015-1741-4.
The original publication is available at http://bmcresnotes.biomedcentral.com
The original publication is available at http://bmcresnotes.biomedcentral.com
Keywords
Methamphetamine abuse -- South Africa, Drug addicts -- Rehabilitation -- South Africa, Drug addicts Rehabilitation -- Mathematical models
Citation
Mushanyu, J., Nyabadza, F. & Stewart, A. G. R. 2015. Modelling the trends of inpatient and outpatient rehabilitation for methamphetamine in the Western Cape province of South Africa. BMC Research Notes, 8:797, doi:10.1186/s13104-015-1741-4