Continuous irrigation as dead space management for fracture related type 1 intramedullary chronic osteomyelitis

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dc.contributor.advisorFerreira, Nandoen_ZA
dc.contributor.advisorBurger, Marilize Cornelleen_ZA
dc.contributor.authorGrey, Jan-Petrusen_ZA
dc.contributor.otherFaculty of Medicine and Health Sciences. Dept. of Surgical Sciences. Orthopaedic Surgery.en_ZA
dc.date.accessioned2023-01-26T06:06:29Zen_ZA
dc.date.available2023-01-26T06:06:29Zen_ZA
dc.date.issued2022en_ZA
dc.descriptionThesis (MMed)--Stellenbosch University, 2023.en_ZA
dc.description.abstractENGLISH ABSTRACT: Introduction: Dead space management following intramedullary debridement and reaming can be challenging and several alternatives have been described. The main objective of this study was to investigate the clinical outcome and resolution rate in patients treated for fracture related Cierny and Mader anatomical type 1 intramedullary chronic osteomyelitis by means of continuous irrigation (modified Lautenbach system) as dead space management following intramedullary reaming. Material and Method: A consecutive series of thirty patients with Cierny and Mader type 1 chronic osteomyelitis, treated between May 2016 and September 2019, were evaluated retrospectively. Patient history and clinical information, including imaging and laboratory results, were reviewed. Treatment procedures and antibiotic profiles were also recorded. Results: The initial cohort included 30 cases with 18 tibias, 11 femurs and one humerus. Seven patients were excluded; three patients did not return for follow up and four patients had less than six months follow up. Of the remaining 23 patients, 91% (21/23) achieved resolution of infection over a median follow up period of 16 months (Interquartile range, IQR 7-21 months). Infecting organisms where isolated in 65% (15/23). The median duration of hospital stay was 6 days (IQR 4-7 days). Post-operative complications were noted in two cases and involved a tibial and femoral refracture, respectively. Both patients however achieved union without recurrence of infection following surgical intervention. Conclusion: Continuous irrigation is a cost-effective single-stage surgical option for dead space management during the treatment of intramedullary chronic osteomyelitis. It provides the advantage of instilling high dose intramedullary antibiotics and negates the need for a second surgical procedure while achieving similar outcomes than other dead space management techniques.en_ZA
dc.description.abstractAFRIKAANSE OPSOMMING: Geen opsomming beskikbaar.af_ZA
dc.description.versionMastersen_ZA
dc.format.extent29 pagesen_ZA
dc.identifier.urihttp://hdl.handle.net/10019.1/126385en_ZA
dc.language.isoen_ZAen_ZA
dc.publisherStellenbosch : Stellenbosch Universityen_ZA
dc.rights.holderStellenbosch Universityen_ZA
dc.subject.lcshOsteomyelitisen_ZA
dc.subject.lcshDead space managementen_ZA
dc.subject.lcshIntramedullary fracture fixationen_ZA
dc.subject.lcshContinuous irrigationen_ZA
dc.subject.lcshChronic diseases -- Alternative treatmenten_ZA
dc.titleContinuous irrigation as dead space management for fracture related type 1 intramedullary chronic osteomyelitisen_ZA
dc.typeThesisen_ZA
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