Post-tuberculosis health-related quality of life, lung function and exercise capacity in a cured pulmonary tuberculosis population in the Breede Valley District, South Africa

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dc.contributor.authorDaniels, Kurt J.en_ZA
dc.contributor.authorIrusen, Elvisen_ZA
dc.contributor.authorPharaoh, Hamiltonen_ZA
dc.contributor.authorHanekom, Susanen_ZA
dc.date.accessioned2021-03-17T08:40:35Z
dc.date.available2021-03-17T08:40:35Z
dc.date.issued2019
dc.descriptionCITATION: Daniels, K. J., et al. 2019. Post-tuberculosis health-related quality of life, lung function and exercise capacity in a cured pulmonary tuberculosis population in the Breede Valley District, South Africa. South African Journal of Physiotherapy, 75(1):a1319, doi:10.4102/sajp.v75i1.1319.
dc.descriptionThe original publication is available at http://www.sajp.co.za
dc.description.abstractBackground: Pulmonary tuberculosis (PTB) remains a major concern worldwide. Albeit curable, PTB continues to negatively affect patients’ health-related quality of life (HRQoL) and functioning even after cure. Objectives: To describe the demographics, respiratory symptoms, pulmonary airflow patterns, HRQoL and exercise capacity of cured PTB patients, in the Breede Valley district of South Africa. Methods: A cross-sectional study conducted at five primary health care facilities included adult patients diagnosed with PTB, who had completed anti-tuberculosis treatment. Post-treatment bronchodilator lung function, HRQoL and 6-min walk distance (6MWD) were measured. Results: Three hundred and twenty-four patients were screened. Specific challenges resulted in 45 patients being included (male n = 25 [56%]; mean population age 39.9 [± 10.2]). HRQoL was assessed using the short-form 12v2, part of the burden of lung disease core questionnaire. In general, self-reported physical scores (physical health component summary score = 45) were higher than mental scores (mental health component summary score = 39). The mean 6MWD was 294.5 m (± 122.7) m (range 110 m – 600 m), which is well below normal reference values. Forty-eight percent (48%) of the sample presented with abnormal lung function, including obstructive (n = 9; 21%), restrictive (n = 11; 25%) and mixed (n = 1; 2%). Conclusions: This pilot study suggests that most cured PTB patients have decreased HRQoL, exercise capacity and abnormal lung function. This study is the first to describe the combination of these three outcomes in a South African population.en_ZA
dc.description.urihttps://sajp.co.za/index.php/sajp/article/view/1319
dc.description.versionPublisher's version
dc.format.extent8 pagesen_ZA
dc.identifier.citationDaniels, K. J., et al. 2019. Post-tuberculosis health-related quality of life, lung function and exercise capacity in a cured pulmonary tuberculosis population in the Breede Valley District, South Africa. South African Journal of Physiotherapy, 75(1):a1319, doi:10.4102/sajp.v75i1.1319
dc.identifier.issn2410-8219 (online)
dc.identifier.issn0379-6175 (print)
dc.identifier.otherdoi:10.4102/sajp.v75i1.1319
dc.identifier.urihttp://hdl.handle.net/10019.1/109671
dc.language.isoen_ZAen_ZA
dc.publisherAOSISen_ZA
dc.rights.holderAuthors retain copyrighten_ZA
dc.subjectPulmonary tuberculosisen_ZA
dc.subjectFunction tests, Pulmonaryen_ZA
dc.subjectRural Healthen_ZA
dc.subjectQuality of life -- Health aspectsen_ZA
dc.titlePost-tuberculosis health-related quality of life, lung function and exercise capacity in a cured pulmonary tuberculosis population in the Breede Valley District, South Africaen_ZA
dc.typeArticleen_ZA
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