ipso-Bromination of tert-butylcalix[4]arenes
Date
2020
Journal Title
Journal ISSN
Volume Title
Publisher
ARKAT USA
Abstract
The ipso-bromination of calix[4]arenes using bromine has been investigated and provides a direct method to
tetra-bromocalix[4]arene in a single step in excellent yield (>90%). The method is also applicable to directly
forming tribromocalix[4]arene in appreciable amounts (>60%). It was found during this study that a number of
important reaction variables were very important for success, namely exclusion of light, temperature control,
purity of starting material, solvent used and rate of bromine addition.
Description
CITATION: Snayer, T. M., Bose, S. & Arnott, G. E. 2020. ipso-Bromination of tert-butylcalix[4]arenes. Arkivoc, v:S1-S7, doi:10.24820/ark.5550190.p011.389.
The original publication is available at https://www.arkat-usa.org
The original publication is available at https://www.arkat-usa.org
Keywords
Organic chemistry, Organobromine compounds, Calixarenes
Citation
Snayer, T. M., Bose, S. & Arnott, G. E. 2020. ipso-Bromination of tert-butylcalix[4]arenes. Arkivoc, v:S1-S7, doi:10.24820/ark.5550190.p011.389.