Anaesthetic management of a three-month-old baby for cervical limited dorsal myeloschisis repair using propofol and alfentanil infusions guided by pharmacokinetic simulation software : case report

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coetzee_anaesthetic_2019.pdf(167.78 KB)
Date
2019
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Medpharm Publications
Abstract
ENGLISH ABSTRACT: We present an uncommon case of limited dorsal myeloschisis in a 3-month-old infant requiring repair guided by intraoperative neuromonitoring (IONM) and therefore avoidance of volatile anaesthetic agents. The case presented challenges in positioning, airway management, a lack of age appropriate pharmacokinetic models in target-controlled infusion (TCI) syringe pumps and unavailability of remifentanil, considered to be an essential drug in this setting. We overcame these challenges using manually controlled infusions of propofol and alfentanil guided by pharmacokinetic simulation software (Stelsim).
Description
CITATION: Coetzee, E., et al. 2019. Anaesthetic management of a three-month-old baby for cervical limited dorsal myeloschisis repair using propofol and alfentanil infusions guided by pharmacokinetic simulation software :a case report. Southern African Journal of Anaesthesia and Analgesia, 25(6):32-35, doi:10.36303/SAJAA.2019.25.6.A5.
The original publication is available at http://www.sajaa.co.za/index.php/sajaa
Keywords
Cervical limited dorsal myeloschisis, Neurophysiologic monitoring, Intravenous anesthesia, Pediatrics -- Anaesthesia
Citation
Coetzee, E., et al. 2019. Anaesthetic management of a three-month-old baby for cervical limited dorsal myeloschisis repair using propofol and alfentanil infusions guided by pharmacokinetic simulation software :a case report. Southern African Journal of Anaesthesia and Analgesia, 25(6):32-35, doi:10.36303/SAJAA.2019.25.6.A5
URI
http://hdl.handle.net/10019.1/109620
Collections
Research Articles (Anaesthesiology and Critical Care)