Release of bacteriocins from nanofibers prepared with combinations of poly(D,L-lactide) (PDLLA) and poly(ethylene oxide) (PEO)
Date
2011
Journal Title
Journal ISSN
Volume Title
Publisher
MDPI
Abstract
Plantaricin 423, produced by Lactobacillus plantarum, and bacteriocin ST4SA produced by Enterococcus mundtii, were electrospun into nanofibers prepared from different combinations of poly(D,L-lactide) (PDLLA) and poly(ethylene oxide) (PEO) dissolved in N,N-dimethylformamide (DMF). Both peptides were released from the nanofibers with a high initial burst and retained 88% of their original antimicrobial activity at 37 °C. Nanofibers have the potential to serve as carrier matrix for bacteriocins and open a new field in developing controlled antimicrobial delivery systems for various applications.
Description
CITATION: Heunis, T., et al. 2011. Release of bacteriocins from nanofibers prepared with combinations of poly(D,L-lactide) (PDLLA) and poly(ethylene oxide) (PEO). International Journal of Molecular Sciences, 12(4):2158-2173, doi:10.3390/ijms12042158.
The original publication is available at http://www.mdpi.com
The original publication is available at http://www.mdpi.com
Keywords
Bacteriocins, Nanofiber, Electrospinning, Antimicrobial activity
Citation
Heunis, T., et al. 2011. Release of bacteriocins from nanofibers prepared with combinations of poly(D,L-lactide) (PDLLA) and poly(ethylene oxide) (PEO). International Journal of Molecular Sciences, 12(4):2158-2173, doi:10.3390/ijms12042158