HIV prevalence in patients with cervical carcinoma : a cohort study at a secondary hospital in South Africa

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dc.contributor.authorMohosho, Mokoena Martinsen_ZA
dc.date.accessioned2023-05-18T12:07:52Zen_ZA
dc.date.available2023-05-18T12:07:52Zen_ZA
dc.date.issued2021en_ZA
dc.descriptionCITATION: Mohosho, M. M. 2021. HIV prevalence in patients with cervical carcinoma : a cohort study at a secondary hospital in South Africa. Medicine, 100(35):e27030, doi:10.1097/MD.0000000000027030.en_ZA
dc.descriptionThe original publication is available at https://journals.lww.comen_ZA
dc.description.abstractThe Human Immunodeficiency Virus (HIV) seropositive prevalence among women with cervical cancer varies in different parts of the world and even within a country. This study aimed to document the prevalence of HIV infection in women with newly diagnosed cervical cancer at a secondary hospital in South Africa. This study is a retrospective review of records of 89 women who were newly diagnosed with cervical cancer between 01 June 2010 and 31 May 2013 at Pelonomi Hospital, Mangaung, South Africa. Data such as age, parity, gravidity, marital status, occupation, HIV status, CD4 count, on anti-retroviral treatment, clinical stage of disease were retrieved from the case files, the Meditech-patient record and Disa laboratory system. Data analysis was done using the SAS statistical package. HIV-seropositive prevalence was 52.4%, with the highest prevalence (91.3%) in the age group 40 years and younger. In HIV-positive women, the mean CD4 cell count was 280 cell/mm3 and 43% of them were not on anti-retroviral treatment. The majority (86%) of all patients presented with late stage disease (International Federation of Gynecology and Obstetrics Stage III and IV) when newly diagnosed with cervical cancer. This study highlights high HIV-seropositive prevalence; severe immunosuppression and late presentation of the disease in women newly diagnosed with cervical cancer. Cervical cancer screening programs need to be fully reinforced into existing HIV health care services to allow for ideal prevention and early detection of the disease. Anti-retroviral treatment needs to be prioritized for HIV-positive women.en_ZA
dc.description.uriPublisher's versionen_ZA
dc.format.extent5 pagesen_ZA
dc.identifier.citationMohosho, M. M. 2021. HIV prevalence in patients with cervical carcinoma : a cohort study at a secondary hospital in South Africa. Medicine, 100(35):e27030, doi:10.1097/MD.0000000000027030.en_ZA
dc.identifier.issn1536-5964 (online)en_ZA
dc.identifier.orcidhttps://orcid.org/0000-0002-0792-2927en_ZA
dc.identifier.otherdoi:10.1097/MD.0000000000027030en_ZA
dc.identifier.urihttp://hdl.handle.net/10019.1/127424en_ZA
dc.language.isoen_ZAen_ZA
dc.publisherWolter Kluwer Healthen_ZA
dc.rights.holderAuthors retain copyrighten_ZA
dc.subjectCervix uteri -- Cancer -- South Africaen_ZA
dc.subjectHIV-positive women -- South Africaen_ZA
dc.subjectCancer -- Diagnosis -- South Africaen_ZA
dc.subjectHealth services administration -- South Africaen_ZA
dc.titleHIV prevalence in patients with cervical carcinoma : a cohort study at a secondary hospital in South Africaen_ZA
dc.typeArticleen_ZA
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