Lupus nephritis. Part I. Histopathological classification, activity and chronicity scores

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dc.contributor.authorBates, W. D.en_ZA
dc.contributor.authorHalland, A.-M.en_ZA
dc.contributor.authorTribe, R. D.en_ZA
dc.contributor.authorRossouw, D. J.en_ZA
dc.date.accessioned2011-03-18T14:57:19Z
dc.date.available2011-03-18T14:57:19Z
dc.date.issued1991
dc.descriptionCITATION: Bates, W. D. et al. 1991. Lupus nephritis. Part I. Histopathological classification, activity and chronicity scores. South African Medical Journal, 79:256-259.
dc.descriptionThe original publication is available at http://www.samj.org.za
dc.description.abstractRenal biopsy has made a major contribution to the understanding and management of patients with lupus nephritis. In a 5-year retrospective study the renal morphology of 55 biopsies from 51 patients with lupus nephritis was classified acccrding to World Health Organisation criteria. In addition, semi-quantitative activity and chronicity scores were documented. The findings were similar to series from other parts of the world. Of the biopsies reviewed, 6 were class II, 13 class III, 32 class IV and 4 class V. In situations of overlap, segmental proliferative features determined the class to which a biopsy specimen was assigned. Twenty-five of the patients, all WHO class IV, showed activity scores in the severe range. Most of the activity score features were common and easily recognised but necrotising angiitis was only seen in 1 patient. Haematoxylin bodies were difficult to document and the nature and value of the haematoxylin body is questioned.
dc.description.versionPublisher’s version
dc.format.extent4 pages
dc.identifier.issn2078-5135 (online)
dc.identifier.issn0256-9574 (print)
dc.identifier.urihttp://hdl.handle.net/10019.1/7332
dc.language.isoen
dc.publisherHealth & Medical Publishing Group
dc.rights.holderSouth African Medical Journal
dc.subjectLupus nephritisen_ZA
dc.titleLupus nephritis. Part I. Histopathological classification, activity and chronicity scoresen_ZA
dc.typeArticle
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