Breast-conserving treatment for stage I and II cancer: tumours excision, axillary dissection, peri-operative interstitial irradiation, with or without peri-operative chemotherapy, followed by breast irradiation - the Tygerberg Hospital experience

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dc.contributor.authorVan Zyl, J. A.en_ZA
dc.contributor.authorMuller, A. G. S.en_ZA
dc.date.accessioned2011-03-18T14:57:22Z
dc.date.available2011-03-18T14:57:22Z
dc.date.issued1989
dc.descriptionCITATION: Van Zyl, J. A. & Muller, A. G. S. 1989. Breast-conserving treatment for stage I and II cancer: tumours excision, axillary dissection, peri-operative interstitial irradiation, with or without peri-operative chemotherapy, followed by breast irradiation - the Tygerberg Hospital experience. South African Medical Journal, 75:519-523.
dc.descriptionThe original publication is available at http://www.samj.org.za
dc.description.abstractSince 1984 breast-conserving treatment has been the treatment of choice for patients at Tygerberg Hospital with early breast cancer. Peri-operative interstitial brachytherapy in breast cancer is described in detail. In the 221 patients treated (225 breasts), 197 breasts received iridium implants and 26 patients received peri-operative chemotherapy (POPFAC). There were 6 recurrences in treated breasts, 3 within the booster area and 3 outside. There were 5 salvage mastectomies, and 1 patient was treated by excision and radiotherapy. Metastases developed in 27 patients. Two patients underwent mastectomy for severe radiation changes and 7 developed postoperative wound infection after POPFAC. Five patients, who had re-excisions and prolonged seroma formation, developed delayed wound infection after POPFAC. Five patients, who had re-excisions and prolonged seroma formation, developed delayed wound infection. The importance of mammography, patient selection, tumour-free margins and radiation dosage are discussed.
dc.description.versionPublisher’s version
dc.format.extent5 pages
dc.identifier.issn2078-5135 (online)
dc.identifier.issn0256-9574 (print)
dc.identifier.urihttp://hdl.handle.net/10019.1/7371
dc.language.isoen
dc.publisherHealth & Medical Publishing Group
dc.rights.holderSouth African Medical Journal
dc.subjectBreast -- Canceren_ZA
dc.titleBreast-conserving treatment for stage I and II cancer: tumours excision, axillary dissection, peri-operative interstitial irradiation, with or without peri-operative chemotherapy, followed by breast irradiation - the Tygerberg Hospital experienceen_ZA
dc.typeArticle
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