Host and microbiome genome-wide association studies : current state and challenges

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dc.contributor.authorAwany, Denisen_ZA
dc.contributor.authorAllali, Imaneen_ZA
dc.contributor.authorDalvie, Shareefaen_ZA
dc.contributor.authorHemmings, Sian M. J.en_ZA
dc.contributor.authorMwaikono, Kilaza S.en_ZA
dc.contributor.authorThomford, Nicholas E.en_ZA
dc.contributor.authorGomez, Andresen_ZA
dc.contributor.authorMulder, Nicolaen_ZA
dc.contributor.authorChimusa, Emile R.en_ZA
dc.date.accessioned2021-11-23T14:16:16Z
dc.date.available2021-11-23T14:16:16Z
dc.date.issued2019
dc.descriptionCITATION: Awany, D., et al. 2019. Host and microbiome genome-wide association studies : current state and challenges. Frontiers in Genetics, 9:637, doi:10.3389/fgene.2018.00637.
dc.descriptionThe original publication is available at https://www.frontiersin.org
dc.description.abstractThe involvement of the microbiome in health and disease is well established. Microbiome genome-wide association studies (mGWAS) are used to elucidate the interaction of host genetic variation with the microbiome. The emergence of this relatively new field has been facilitated by the advent of next generation sequencing technologies that enable the investigation of the complex interaction between host genetics and microbial communities. In this paper, we review recent studies investigating host–microbiome interactions using mGWAS. Additionally, we highlight the marked disparity in the sampling population of mGWAS carried out to date and draw attention to the critical need for inclusion of diverse populations.en_ZA
dc.description.urihttps://www.frontiersin.org/articles/10.3389/fgene.2018.00637/full
dc.description.versionPublisher's version
dc.format.extent12 pages ; illustrations
dc.identifier.citationAwany, D., et al. 2019. Host and microbiome genome-wide association studies : current state and challenges. Frontiers in Genetics, 9:637, doi:10.3389/fgene.2018.00637
dc.identifier.issn1664-8021(online)
dc.identifier.otherdoi:10.3389/fgene.2018.00637
dc.identifier.urihttp://hdl.handle.net/10019.1/123494
dc.language.isoen_ZAen_ZA
dc.publisherFrontiers Media
dc.rights.holderAuthors retain copyright
dc.subjectMicrobiomeen_ZA
dc.subjectMicrobiotheria -- Researchen_ZA
dc.subjectGenomicsen_ZA
dc.titleHost and microbiome genome-wide association studies : current state and challengesen_ZA
dc.typeArticleen_ZA
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