Low plasma pyridoxal-5'-phosphate levels in children with the nephrotic syndrome

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dc.contributor.authorVan Buuren, A. J.en_ZA
dc.contributor.authorShephard, G. S.en_ZA
dc.contributor.authorLabadarios, D.en_ZA
dc.date.accessioned2011-03-18T14:57:36Z
dc.date.available2011-03-18T14:57:36Z
dc.date.issued1985
dc.descriptionCITATION: Van Buuren, A. J., Shephard, G. S. & Labadarios, D. 1985. Low plasma pyridoxal-5'-phosphate levels in children with the nephrotic syndrome. South African Medical Journal, 61:329-332.
dc.descriptionThe original publication is available at http://www.samj.org.za
dc.description.abstractOf 35 children with the nephrotic syndrome in relapse, 88% were found to have low circulating plasma pyridoxal-5'-phosphate (PLP) levels. Remission of the syndrome was associated with spontaneous normalization of plasma PLP levels in 23 such children. A significant (P < 0.001) positive correlation (r = 0.81) was found between plasma albumin and PLP levels and a significant (P < 0.001) negative correlation (r = -0.66) between plasma PLP and serum cholesterol levels. The low plasma PLP levels may be due to enhanced urinary excretion of albumin-bound PLP in view of the severe proteinuria which characterizes the nephrotic syndrome.
dc.description.versionPublisher’s version
dc.format.extent4 pages
dc.identifier.issn2078-5135 (online)
dc.identifier.issn0256-9574 (print)
dc.identifier.urihttp://hdl.handle.net/10019.1/7525
dc.language.isoen
dc.publisherHealth & Medical Publishing Group
dc.rights.holderSouth African Medical Journal
dc.subjectKidneys -- Diseasesen_ZA
dc.titleLow plasma pyridoxal-5'-phosphate levels in children with the nephrotic syndromeen_ZA
dc.typeArticle
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