A cluster randomized controlled trial evaluating the efficacy of peer mentors to support South African women living with HIV and their infants

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dc.contributor.authorRotheram-Borus, Mary Janeen_ZA
dc.contributor.authorRichter, Linda M.en_ZA
dc.contributor.authorVan Heerden, Alastairen_ZA
dc.contributor.authorVan Rooyen, Heidien_ZA
dc.contributor.authorTomlinson, Marken_ZA
dc.contributor.authorHarwood, Jessica M.en_ZA
dc.contributor.authorComulada, W. Scotten_ZA
dc.contributor.authorStein, Alanen_ZA
dc.date.accessioned2016-03-09T09:19:10Z
dc.date.available2016-03-09T09:19:10Z
dc.date.issued2014-01-22
dc.descriptionCITATION: Rotheram-Borus, M. J. et al. 2014. A cluster randomized controlled trial evaluating the efficacy of peer mentors to support South African women living with HIV and their infants. PLoS ONE, 9(1):e84867, doi:10.1371/journal.pone.0084867.
dc.descriptionThe original publication is available at http://journals.plos.org/plosone
dc.description.abstractObjective: We evaluate the effect of clinic-based support by HIV-positive Peer Mentors, in addition to standard clinic care, on maternal and infant well-being among Women Living with HIV (WLH) from pregnancy through the infant's first year of life. Methods: In a cluster randomized controlled trial in KwaZulu-Natal, South Africa, eight clinics were randomized for pregnant WLH to receive either: a Standard Care condition (SC; 4 clinics; n = 656 WLH); or an Enhanced Intervention (EI; 4 clinics; n = 544 WLH). WLH in the EI were invited to attend four antenatal and four postnatal meetings led by HIV-positive Peer Mentors, in addition to SC. WLH were recruited during pregnancy, and at least two post-birth assessment interviews were completed by 57% of WLH at 1.5, 6 or 12 months. EI's effect was ascertained on 19 measures of maternal and infant well-being using random effects regressions to control for clinic clustering. A binomial test for correlated outcomes evaluated EI's overall efficacy. Findings: WLH attended an average of 4.1 sessions (SD = 2.0); 13% did not attend any sessions. Significant overall benefits were found in EI compared to SC using the binomial test. Secondarily, over time, WLH in the EI reported significantly fewer depressive symptoms and fewer underweight infants than WLH in the SC condition. EI WLH were significantly more likely to use one feeding method for six months and exclusively breastfeed their infants for at least 6 months. Conclusions: WLH benefit by support from HIV-positive Peer Mentors, even though EI participation was partial, with incomplete follow-up rates from 6–12 months.en_ZA
dc.description.urihttp://journals.plos.org/plosone/article?id=10.1371/journal.pone.0084867
dc.description.versionPublisher's version
dc.format.extent9 pages
dc.identifier.citationRotheram-Borus, M. J. et al. 2014. A cluster randomized controlled trial evaluating the efficacy of peer mentors to support South African women living with HIV and their infants. PLoS ONE, 9(1):e84867, doi:10.1371/journal.pone.0084867.
dc.identifier.issn1932-6203 (online)
dc.identifier.otherdoi:10.1371/journal.pone.0084867
dc.identifier.urihttp://hdl.handle.net/10019.1/98270
dc.language.isoen_ZAen_ZA
dc.publisherPLoS
dc.rights.holderAuthors retain copyright
dc.subjectHIV-positive pregnant womenen_ZA
dc.subjectPregnant women -- Health and hygieneen_ZA
dc.subjectCaregiversen_ZA
dc.subjectPrenatal careen_ZA
dc.subjectMaternal health servicesen_ZA
dc.subjectMentoring in health servicesen_ZA
dc.titleA cluster randomized controlled trial evaluating the efficacy of peer mentors to support South African women living with HIV and their infantsen_ZA
dc.typeArticleen_ZA
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