Important causes of chronic kidney disease in South Africa

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dc.contributor.authorMoosa, M. R.en_ZA
dc.contributor.authorVan der Walt, I.en_ZA
dc.contributor.authorNaicker, S.en_ZA
dc.contributor.authorMeyers, A. M.en_ZA
dc.date.accessioned2016-07-28T08:33:34Z
dc.date.available2016-07-28T08:33:34Z
dc.date.issued2015
dc.descriptionCITATION: Moosa, M. R., et al. 2015. Important causes of chronic kidney disease in South Africa. South African Medical Journal, 105(4):320, doi:10.7196/SAMJ.9535.
dc.descriptionThe original publication is available at http://www.samj.org.za
dc.description.abstractIn hypertensive patients without chronic kidney disease (CKD) the goal is to keep blood pressure (BP) at ≤140/90 mmHg. When CKD is present, especially where there is proteinuria of ≥0.5 g/day, the goal is a BP of ≤130/80 mmHg. Lifestyle measures are mandatory, especially limitation of salt intake, ingestion of adequate quantities of potassium, and weight control. Patients with stages 4 - 5 CKD must be carefully monitored for hyperkalaemia and deteriorating kidney function if angiotensin-converting enzyme (ACE) inhibitors or angiotensin II receptor blockers (ARBs) are used, especially in patients >60 years of age with diabetes or atherosclerosis. BP should be regularly monitored and, where possible, home BP-measuring devices are recommended for optimal control. Guidelines on the use of antidiabetic agents in CKD are presented, with the warning that metformin is contraindicated in patients with stages 4 - 5 CKD. There is a wide clinical spectrum of renal disease in the course of HIV infection, including acute kidney injury, electrolyte and acid-base disturbances, HIV-associated glomerular disease, acute-on-chronic renal disease and side-effects related to the treatment of HIV.en_ZA
dc.description.abstractAFRIKAANSE OPSOMMING: Geen opsomming beskikbaaraf_ZA
dc.description.urihttp://www.samj.org.za/index.php/samj/article/view/9535
dc.description.versionPublisher's version
dc.format.extent8 pagesen_ZA
dc.identifier.citationMoosa, M. R., et al. 2015. Important causes of chronic kidney disease in South Africa. South African Medical Journal, 105(4):320, doi:10.7196/SAMJ.9535
dc.identifier.issn2078-5135 (online)
dc.identifier.issn0256-9574 (print)
dc.identifier.otherdoi:10.7196/SAMJ.9535
dc.identifier.urihttp://hdl.handle.net/10019.1/99264
dc.language.isoen_ZAen_ZA
dc.publisherHealth & Medical Publishing Groupen_ZA
dc.rights.holderHealth & Medical Publishing Groupen_ZA
dc.subjectChronic kidney diseaseen_ZA
dc.subjectKidneys -- Diseasesen_ZA
dc.subjectHypertensionen_ZA
dc.subjectChronic renal failure -- Causesen_ZA
dc.titleImportant causes of chronic kidney disease in South Africaen_ZA
dc.typeArticleen_ZA
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