Prevalence of primary papillary peritoneal neoplasia in patients with ovarian carcinoma
Date
1985-06
Authors
Lindeque, B. G.
Cronje, H. S.
Deale, C. J. C.
Journal Title
Journal ISSN
Volume Title
Publisher
Health and Medical Publishing Group (HMPG)
Abstract
Primary papillary peritoneal neoplasia (PPPN) is a recently recognized disease entity. Macroscopically it resembles ovarian carcinoma. On microscopic examination it also superficially resembles serous ovarian adenocarcinoma, but in PPPN the epithelial cells are single-layered and well differentiated with very rare mitoses, and numerous psammoma bodies are found. In a retrospective review of 61 consecutive patients with serous or papillary ovarian adenocarcinoma seen over a 7-year period, 4 patients with PPPN were found (6.5%). One of these patients was in clinical stage I, 2 were in stage II and 1 was in stage III. All had undergone total abdominal hysterectomy and bilateral salpingo-oophorectomy. Two of these patients received additional chemotherapy and 1 radiotherapy. After 3, 3, 8 and 4 years there were no recurrences in these patients, in contrast to a 29.1% 5-year survival rate for the other patients with serous carcinoma. Cytological examination of ascitic fluid specimens performed in 3 of the 4 patients with PPPN demonstrated the presence of highly differentiated serous tufted cells.
Description
The original publication is available at http://archive.samj.org.za/
Article
Article
Keywords
Ovaries -- Cancer
Citation
Lindeque, B. G., Cronje, H. S. & Deale, C. J. C. 1985. Prevalence of primary papillary peritoneal neoplasia in patients with ovarian carcinoma. South African Medical Journal, 67(25):1005-1007.