Browsing by Author "Schraader, E. B."

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    Pleuropericardial effusions in children with non-Hodgkin's lymphoma. A report of 2 cases
    (Health & Medical Publishing Group, 1987-12) Schraader, E. B.; Hesseling, P. B.
    Two children with non-Hodgkin's lymphoma (NHL) who presented with pleuropericardial effusions are reported on. Pericardial effusions are very unusual in children with mediastinal nodal NHL. In the first patient, who presented with a pleural effusion and pericardial tamponade, the diagnosis of NHL was obscured by a false-positive report of acid-fast bacilli in the pleural fluid. The second patient presented with a pleural effusion and a pericardial effusion with superior vena cava obstruction. Rapid filling of the serous cavities was a striking feature in both cases. Cytological and biochemical investigation of the pleural fluid and pleural biopsy are of limited diagnostic value. Pleuropericardial effusions in NHL are reviewed. The patients have been in disease-free remission for 18 and 16 months respectively.
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    A prospective study of long-term use of amikacin in a paediatrics department : indications, administration, side-effects, bacterial isolates and resistance
    (Health & Medical Publishing Group, 1990) Hesseling, P. B.; Mouton, W. L.; Henning, P. A.; Kirsten, G. F.; Spruyt, L. L.; Schraader, E. B.; Wessels, G.; Grassman, R.
    Amikacin (Amikin; B-M) was used as the only aminoglycoside for 18 months in a paediatric department within a general hospital because of high levels of resistance of Klebsiella pneumoniae, Pseudomonas aeruginosa and Enterobacter cloacae isolates to tobramycin, gentamicin and netilmicin. Between 1 February 1987 and 31 July 1988, 816 children were treated with a slow intravenous injection at a standardised dose adjusted for weight and age. Respiratory disease was present in 35,8% of 537 neonates, 56,4% of 190 infants and 70,9% of 89 older children. Escherichia coli (65 isolates), Klebsiella species (59 isolates), Enterobacter species (26 isolates) and P. aeruginosa (22 isolates) constituted the most common Gram-negative pathogens. The positive blood culture yield was 7,8%. Satisfactory median peak and trough serum amikacin levels were achieved. No significant renal side-effects were noted. Severe bilateral hearing loss in 1 low-birthweight infant resulted from inadvertent overdosage. At the end of this 18-month surveillance period 97,7% of E. coli, 98,6% of K. pneumoniae, 96,3% of E. cloacae, and 98,0% of P. aeruginosa isolates remained sensitive to amikacin, while resistance of K. pneumoniae to tobramycin, netilmicin and gentamicin decreased significantly (P < 0,003, P < 0,001 and P < 0,007 respectively; chi-square test).
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    Reflex neurovascular dystrophy. A case report
    (Health & Medical Publishing Group, 1987-07) Schraader, E. B.
    A child suffering from reflex neurovascular dystrophy (RND) who presented with a bizarre neurological picture is reported. RND is an extremely painful and disabling condition readily amenable to treatment. A striking feature is the localisation of pain and hyperaesthesia which do not follow a somatic dermatome distribution.