Browsing by Author "Louwrens, H. D."

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    Endoscopic investigation for gastric cancer in a high-risk group
    (Health & Medical Publishing Group, 1992) Louwrens, H. D.; Jaskiewicz, K.; Van Wyk, M. J.; Kotze, T. J. V. W.; Brits, T. A.
    Early gastric cancer (EGC) was diagnosed in only a small percentage (<1%) of gastric cancer cases seen at Tygerberg Hospital over a 10-year period (1976-1985). This study, aimed at increasing the yield of EGC, was conducted in some high-incidence areas for gastric cancer. Coloured men, who are at high risk for gastric cancer, were identified by their medical practitioners and investigated. A total of 272 coloured males with nonspecific foregut symptoms underwent upper gastro-intestinal endoscopy and multiple biopsy specimens were obtained from all localised mucosal lesions. Twelve gastric cancers were histologically verified, of which 11 were diagnosed in males over 40 years of age. Two EGCs were diagnosed in older males, resulting in a markedly higher proportion of EGC in this subgroup (18,2%) than the proportion of EGC in inpatients at our institution (0,9%). Twenty-two per cent of males over 40 years of age had gastric ulcers compared with 9,2%. of younger males. Chronic atrophic gastritis was present in 56,2% of older males but in only 24,6% of younger males. Those over 40 years of age emerged as a subgroup with a high prevalence of gastric cancer and EGC, and concomitant conditions.
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    Has the character of gastric cancer changed? a descriptive study of a 10-year period
    (Health & Medical Publishing Group, 1991) Louwrens, H. D.; Van Kotze, W. T. J.; Brits, D. A.; Rossouw, D. J.; Falck, V.
    Over the 10-year period January 1976-December 1985, 446 patients with histologically verified adenocarcinoma of the stomach were treated at Tygerberg Hospital. Coloured patients made up 63.4% of the study population and a significant increase in the annual proportion of this group was observed. Coloured men comprised 47.6% of the total group. The mean age of white and coloured patients differed significantly (68.9 v. 56.5; P<0.001). The symptom complex was essentially similar in the two racial groups and in general the character of the symptoms had no bearing on the prevalence of resection. Although antral tumours were most common in whites and in coloureds, there was a significant increase in tumours located in the fundus in whites. The resection rate remained unchanged over the 10-year period. Only 4 cases of early gastric cancer were detected during this period without any signs of an increased yield of early lesions over time. This audit revealed no beneficial changes over time, which is in stark contrast with reports from Japan regarding the proportion of curable lesions.
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    Subjective pulsatile tinnitus cured by carotid endarterectomy
    (Health & Medical Publishing Group, 1989-05) Louwrens, H. D.; Botha, J.; Van der Merwe, D. M.
    A 70-year-old woman with unilateral pulsatile tinnitus was relieved of the complaint after carotid endarterectomy. Internal carotid artery stenosis presenting with pulsatile tinnitus is rare. Endarterectomy can relieve symptoms if the correct diagnosis is made.