Browsing by Author "Goldberg, P. A."

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    Inherited colon cancers
    (Health & Medical Publishing Group, 2000) Goldberg, P. A.; Madden, M. V.; Harocopos, C.; Grobbelaar, J. J.; Kotze, M. J.; Marx, M. P.; De Jong, G.
    Grobbelaar et al.' and Ramesar et al.' (in this issue) have identified germline mutations in certain families with h"o different types of inherited colorectal cancers. This means that blood tests are now available in South Africa for clinical use in these particular families. Within the families these DNA-based tests can separate individuals with the mutation that causes cancer from those who do not have it. Those with a mutation may pass the family-specific mutation to their children.