Browsing by Author "Botha, D."

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    Disseminated tuberculosis, bone marrow necrosis and lymphoma : a case report
    (Health & Medical Publishing Group, 1977) Staples, W. G.; Getaz, E. P.; Botha, D.
    Tuberculosis often complicates lymphoma, and bone marrow necrosis has been described in disseminated tuberculosis. However, the association of lymphoma, disseminated tuberculosis and bone marrow necrosis is rare. We report a patient with this triple association. After a 3-week influenza-like illness the patient was admitted to hospital semicomatose with pancytopenia and hyponatraemia. During routine examination a bone marrow trephine biopsy revealed diffuse lymphomatous infiltration with scattered necrotic foci. On Ziehl-Neelsen staining these foci exhibited numerous acid-fast bacilli. The patient subsequently died and at autopsy was found to have widely disseminated non-reactive tuberculosis.
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    Knowledge management practices in the South African business sector : preliminary findings of a longitudinal study
    (AOSIS, 2002) Botha, D.; Fouche, B.
    This article reports the findings of the first phase of a longitudinal research project on knowledge management (KM) practices in the South African business sector. The overall objectives of the research are to describe prevalent knowledge management practices, to identify patterns and trends, and to develop knowledge management benchmarking and strategic management tools for the business sector. During the first phase of the project a data collection and analysis instrument for a recurring survey of knowledge management practices was developed and verified. The statistical verification of the instrument was based on a pilot survey of seventy-four respondents representing fifty-three companies in the South African industry, using one-way analysis of variance, cross-tabular chi-squared tests and principal component analysis. The data collected during the pilot survey was considered to be sufficient for a first order analysis of KM practices. The survey tested respondent perceptions on six factors scored by aggregation from 24 indicators. The selection of the factors and indicators was based on a KM reference model developed for the purpose of the research. The findings indicated clear patterns of organisational performance related to the factors of the model. The patterns corroborated to a large extent the published findings of research on KM practices in industrialised countries. This provided the confidence to use the preliminary findings as the basis of hypotheses to guide the further phases of the project.
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    Systemic lupus erythematosus with coronary vasculitis and massive myocardial infarction : a case report
    (Health and Medical Publishing Group (HMPG), 1986-07) Przybojewski, J. Z.; Botha, D.; Klopper, J. F.
    A 32-year-old white woman presented with angina pectoris and an acute myocardial infarction (MI) complicated by congestive cardiac failure. Other symptoms and results of immunological investigation were highly suggestive of systemic lupus erythematosus (SLE). Thallium-201 scintigraphy confirmed an extensive MI, as initially suspected from an ECG. Cardiac catheterization delineated a poorly contracting left ventricle secondary to MI. Selective coronary angiography showed features suspicious of coronary arteritis involving the left anterior descendingand left circumflex coronary arteries. Right ventricular endomyocardial biopsy failed to show any 'small·vessel disease', vasculitis or myocarditis. We suggest that the acute MJ was caused by coronary arteritis due to SLE. Overview of the literature indicates that coronary arteritis is not as rare a complicatiqp of SLE as previously believed; however, acute MHs most unusual.