Research Articles (Gastroenterology)

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Browsing Research Articles (Gastroenterology) by Author "Bezuidenhout, D. J. J."

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    A comparison of 4-week peptic ulcer healing rates following treatment with antacids and ranitidine
    (Health and Medical Publishing Group (HMPG), 1984-06) Bezuidenhout, D. J. J.; Perold, J. G.; Adams, G.
    Eighty-eight patients with endoscopically proven gastric and duodenal ulceration were treated with ranitidine (Zantac; Glaxo) or an antacid preparation containing aluminium hydroxide and magnesium trisilicate (Gelusil; Warner) over a 4-week period to assess healing. Clinical, haematological and biochemical assessment and endoscopy were performed at the beginning and at the end of this period. Of the duodenal ulcers, 74% healed on ranitidine therapy and 63% on Gelusil. This difference was not statistically significant (χ2(1) = 0,55). Of the gastric ulcers 58% healed on ranitidine therapy and 35% on Gelusil, but this difference did not reach statistical significance (χ2(1) = 1,79). There was no significant difference between the two therapies with regard to symptomatic relief in the duodenal ulcer group, but ranitidine produced significantly better results in the gastric ulcer group. No side-effects were noted in either group.
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    Folate levels in patients with ulcerative colitis receiving sulphasalazine
    (Health & Medical Publishing Group, 1984) Schoeman, M.; Bezuidenhout, D. J. J.
    The question of folate deficiency in patients receiving sulphasalazine is still controversial. A random sample of patients with ulcerative colitis receiving sulphasalazine were studied to determine the clinical significance of the inhibition of folic acid absorption by the drug. No significant lowering of folate levels could be determined.
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    Hydatid cysts simulating massive ascites : a case report
    (Health & Medical Publishing Group, 1986) Adams, G.; Bezuidenhout, D. J. J.
    A patient with the clinical features of massive ascites was found to have extensive intra-abdominal hydatid cysts.