Central Analytical Facility

Permanent URI for this community

Now showing 1 - 1 of 1

Characterization and cardiovascular effects of (13S)-9α,13α-epoxylabda-6β(19),15(14)diol dilactone, a diterpenoid isolated from Leonotis leonurus
(University of KwaZulu-Natal, 2008) Obikeze, Kene C.; McKenzie, Jean M.; Green, Ivan R.; Mugaboa, Pierre
A new diterpenoid, (13S)-9α,13α-epoxylabda-6β(19),15(14)diol dilactone (1), was isolated from Leonotis leonurus and the structure determined via NMR analysis. The compound causes significant changes in blood pressure of anaesthetized normotensive rats and exhibits a negative chronotropic effect.