BOOK BLURB: Statistical data confirms beyond a doubt that sub-Saharan Africa is a very poor region with the highest HIV/AIDS prevalence in the world. The region has poor and limited health facilities and resources (personnel and financial). such a scenario is conducive to the increase of the HIV/AIDS pandemic. HIV/AIDS and poverty are intricately linked and they interplay. Responding effectively to the situation requires a relevant, applicable and holistic model. This publication carefully describes the HIV/AIDS pandemic and how it is understood in some African contexts, which hampers prevention initiatives. Is also delineates the complex nature of the poverty and HIV/AIDS interplay. To address the situation, a family systems practical ecclesiological theology and approach to HIV/AIDS ministry, and a pastoral counselling approach that derives from and is sensitive to the African context, are proposed. The proposed model comprises congregational home-based pastoral care that integrates the church and African extended family systems for effective HIV/AIDS ministry.